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세부과제번호
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2016M3A9D5A01952416
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단계
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2단계 2차년도
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세부과제명
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유전자변형마우스 병리표현형 분석서비스시스템 구축 및 운용
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공동 유/무
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N
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SCI여부
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Y
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게재년월
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-
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논문제목
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Increased expression of stemness markers and altered tumor stroma in hepatocellular carcinoma under TACE-induced hypoxia: A biopsy and resection matched study.
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총저자명
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Ji Hae Nahm, Hyungjin Rhee, Haeryoung Kim, Jeong Eun Yoo, Jee San Lee, Youngsic Jeon, Gi Hong Choi, Young Nyun Park
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학술지명
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Oncotarget
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게재권(호)
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8(59)
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저널구분
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-
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페이지수
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99359-99371
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참여연구원
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-
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연구책임자
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남기택
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과제기여도
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30
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PMID
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29245907
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사사기관수
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-
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IF (년도)
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5.168
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제1저자
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Ji Hae Nahm
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교신저자
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Young Nyun Park
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공동저자
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Hyungjin Rhee, Haeryoung Kim, Jeong Eun Yoo, Jee San Lee, Youngsic Jeon, Gi Hong Choi
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초록
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Hepatocellular carcinomas (HCCs) expressing stemness markers are characterized by an aggressive behavior, which might be promoted by an altered tumor stroma. Transarterial chemoembolization (TACE) induces severe hypoxia, and its effect on stemness and tumor stroma of HCCs remains unclear. The purpose of this study was to evaluate the sequential changes of stemness and tumor stroma under TACE-induced hypoxia using biopsy and resection-matched HCCs.
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